7 - 10 December

ASH 2024

SAN DIEGO

Gilead & Kite at ASH 2024

At ASH 2024, we are excited to share new data across different therapies and indications, soliditying our goal to bring the promise of cell therapy to as many eligible patients as possible. Learn more about the cell therapy sponsored and supported/collaborative studies below.

Some of the abstracts below refer to therapies and/or indications that are investigational and their satety and efficacy have not been established.

2L+ R/R LBCL
526

Real-Word Early Outcomes of Second-Line Axi-Cel Therapy in Patients with R/R LBCL 

Dasom (Caroline) Lee, et al.
SUNDAY DEC 8 10:15 AM
SESSION 906 9:30 AM - 11:00 AM Pacific Ballroom 24-26
3L R/R LBCL
527

Real-world Trends of Cytokine Release Syndrome and Neurologic Events, and Pattern of Their Management Among Patients Receiving Axi-cel for R/R LBCL in the US: A CIBMTR Report 

Jiasheng Wang, et al.
SUNDAY DEC 8 10:30 AM
SESSION 623 09:30 AM - 11:00 AM Pacific Ballroom 24-26
3L R/R LBCL
609

Predictors of Early Safety Outcomes with Axi-Cel in Patients with R/R LBCL

Christopher Sun Strouse, et al.
SUNDAY DEC 8 12:30 PM
SESSION 623 12:00 PM - 1:30 PM Grand Ballroom 2-4
R/R MCL
748

Primary Analysis of ZUMA-2 Cohort 3: Brexucabtagene Autoleucel (Brexu-Cel) in Patients (Pts) With Relapsed/ Refractory Mantle Cell Lymphoma (R/R MCL) Who Were Naive to Bruton Tyrosine Kinase Inhibitors (BTKi)

Tom van Meerten, et al.
MONDAY DEC 9 11:15 AM
SESSION 623 10:30 AM – 12:00 PM Grand Ballroom 8-9
FL
864

5-Year Follow-up Analysis From ZUMA-5: A Phase 2 Trial of Axi-Cel in Patients With R/R Indolent Non-Hodgkin Lymphoma 

Sattva Neelapu, et al
MONDAY DEC 9 4:00 PM
SESSION 623 2:45 PM – 4:15 PM Grand Ballroom 11-13

2031 Collab

Early MRD detection after CAR-T Associated with Poor Outcome in in Patients with Large B-Cell Lymphoma*

Nira Krasnow, et al.
SATURDAY DEC 7
SESSION 702 5:30 PM – 7:30 PM
2367

Treatment Patterns and Predictors of Survival after First Line Therapy in Large B-Cell Lymphoma in a Real-World US Cohort 

Joseph McGuirk, et al.
SATURDAY DEC 7
SESSION 622 5:30 PM – 7:30 PM
3477

Improvements in Axicabtagene Ciloleucel Manufacturing Result in High Delivery Success and More Predictable Turnaround Time for Patients With Relapsed/Refractory Large B-Cell Lymphoma 

David Miklos, et al.
SUNDAY DEC 8
SESSION 711 6:00 PM – 8:00 PM
3481

KITE-753: An Autologous Rapid Manufactured Anti-CD19/ CD20 CAR-T Product for the Treatment of B-cell Malignancies 

Jodi Murakami, et al.
SUNDAY DEC 8
SESSION 711 6:00 PM – 8:00 PM
3734 Collab

The Patient Journey and Treatment Outcomes Comparing Inpatient Versus Outpatient Axicabtagene Ciloleucel in Non- Hodgkin’s Lymphoma (NHL) - a Large, Multicenter Study) 

Minoo Battiwalla, et al.
SUNDAY DEC 8
SESSION 906 6:00 PM – 8:00 PM
4193

Impact of Disease Burden, CAR-T Expansion, and Mononuclear Cell Recovery on Overall Response and Duration of Response in ZUMA-3 Pivotal Study 

Sabina Adhikary, et al.
MONDAY DEC 9
SESSION 613 6:00 PM – 8:00 PM
4368

Impact of Inflammation, Tumor and Product Attributes on Clinical Outcomes in Patients with Relapsed/Refractory Follicular Lymphoma Treated with Axicabtagene Ciloleucel 

Soumya Poddar, et al.
MONDAY DEC 9
SESSION 622 6:00 PM – 8:00 PM
4388

Five-Year Outcomes of Patients (Pts) With Relapsed/Refractory Mantle Cell Lymphoma (R/R MCL) Treated With Brexucabtagene Autoleucel (Brexu-cel) in ZUMA-2 Cohorts 1 and 2 

Michael Wang, et al.
MONDAY DEC 9
SESSION 623 6:00 PM – 8:00 PM
4721

Health Related Quality of Life (HRQoL) in Relapsed/Refractory Multiple Myeloma (RRMM): A Systematic Literature Review (SLR) and Meta-Analysis

Rahul Banerjee, et al.
MONDAY DEC 9
SESSION 653 6:00 PM – 8:00 PM
4825

Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Patients With Relapsed and/or Refractory Multiple Myeloma (RRMM): Efficacy and Safety With 34-Month Median Follow-up

Michael Bishop, et al.
MONDAY DEC 9
SESSION 704 6:00 PM – 8:00 PM
5037

Estimating the Impact on Survival of Not Receiving CAR T Therapy Despite Being Eligible in Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL) Patients in Germany

Veit Bücklein, et al.
MONDAY DEC 9
SESSION 902 6:00 PM – 8:00 PM
5092

Real-World (RW) Outcomes for Brexucabtagene Autoleucel (Brexu-Cel) Treatment in Patients (Pts) With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia (R/R B-ALL) by High-Risk Features and Prior Treatments: Updated Evidence From the CIBMTR® Registry

Kistada Wudhikarn, et al.
MONDAY DEC 9
SESSION 906 6:00 PM – 8:00 PM
2914

Mutational Landscape and Depth of Response In Patients With Acute Myeloid Leukemia (AML) Treated With Magrolimab in Combination with Venetoclax and Azacitidine Compared to Placebo

L Johnson, et al.
SUNDAY DEC 8
SESSION 618 6:00 PM – 8:00 PM
4604

Impact of mutational landscape and CD47 levels in the magrolimab + azacitidine vs placebo + azacitidine trial in patients with untreated higher risk myelodysplastic syndrome

Lisa Johnson and Yajia Zhang
MONDAY DEC 9
SESSION 637 6:00 PM – 8:00 PM
4160

Effects of Magrolimab Therapy in Conjunction with Conventional Chemotherapeutics in Pediatric Acute Myeloid Leukemia Patient Derived Xenograft Models

Sohani Sandhu, et al.
MONDAY DEC 9
SESSION 604 6:00 PM – 8:00 PM
2019

Anti-CD117 plus anti-SIRPa or Fc-silenced anti-CD47 enables hematopoietic stem cell depletion and syngeneic engraftment without development of severe anemia

Stepen Persaud, et al.
SATURDAY DEC 7
SESSION 701 5:30 PM – 7:30 PM

6962

Treatment Patterns and Outcomes in Triple-Class Exposed Patients with Relapsed and Refractory Multiple Myeloma: Findings from the Flatiron Database 

Surbhi Sidana, et al
7159

In Vitro and In Vivo Characterization of Axicabtagene Ciloleucel Identifies Features Associated with Treatment Resistance in Patients, Including a Dysfunctional CD8+ T Cell State Characterized by Overexpression of GATA3 Transcript 

Surbhi Sidana, et al
7592

A United States (US) Cost-Effectiveness Analysis of Axicabtagene Ciloleucel Compared to Odronextamab in Third Line or Later (3L+) Diffuse Large B-Cell Lymphoma 

Frederick L Locke, et al
7607

Short-term Costs Associated With Outpatient Use of Axicabtagene Ciloleucel in Second-line Relapsed/ Refractory Large B-cell Lymphoma Based on ZUMA-24 Clinical Trial 

Olalekan Oluwole, et al
7775

Real-World Interim PET/CT Scan Use During Frontline (1L) Therapy and Subsequent Treatment Characteristics in Patients with Refractory Diffuse Large B-Cell Lymphoma (DLBCL) 

Ran Reshef, et al

This medicine is subject to additional monitoring. This will allow quick identification of new safety information. You can help by reporting any side effects you may get.

Reporting of side effects 
If you get any side effects, talk to your doctor or nurse. In Great Britain and Northern Ireland, you can also report side effects directly via the Yellow Card Scheme, Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. You can also report side effects and quality complaints to Gilead. For information now how to report a side effect in another country, click here. By reporting side effects, you can help provide more information on the safety of this medicine.